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primary difference between brands is that each brand has different fillers and binders, and some patients may have allergies to some brands, or pill dosage sizes, versus others..is the most commonly prescribed thyroid hormone replacement drug. 50 mcg size pills are morelikely to be hypoallergenic and dye-free for most manufacturers. most doctors do not recommend the generic version of this drug, but the different brand names are considered bioequivalent in terms of effectiveness

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