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Slowing the heart rate also reduces the energy used by the heart to pump blood around the body. This in turn reduces the heart's need for oxygen. At the same time, widening the blood vessels improves the blood and therefore oxygen supply to the heart. Both these features mean that diltiazem can be used in the management of angina. The chest pain of angina is caused by insufficient oxygen supply to the heart. As diltiazem improves this oxygen supply, and also reduces the effort the heart has to make to pump blood, it can be used to prevent angina attacks. Diltiazem capsules are a long-acting or 'modified-release' form of diltiazem. This means that they are designed to release the diltiazem slowly and continuously over several hours to produce a steady blood level of the medicine throughout the day. Diltiazem capsules are designed to be taken once a day, at the same time each day. They should be swallowed whole and not chewed or crushed, as this would damage the modified-release action. 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